The Scheme aims to assess the overall quality of diagnostic analysis performed by a laboratory by a combination of retrospective audit and distribution of reference material or web-based EQA. It assesses tissue specific performance for Constitutional cases and for Oncology cases (acquired abnormalities.)

Performance criteria have been divided into three broad inter-linked categories:

  1. Technical performance
    Slide quality. The banding quality of submitted slides is assessed.
  2. Analytical performance:
    Scoring of the quality of individual laboratory analyses and description of ISCN either as a result of retrospective external audit of cases requested by the scheme and/or external assessment (the distribution of suitable reference material for proficiency testing).
  3. Interpretative performance:
    Scoring of the quality of individual laboratory reports either as a result of retrospective external audit of cases by the scheme or by external assessment (web based EQA).

UK laboratories will be given a score against these criteria under NQAAP-determined performance standards Non-UK laboratories are also scored against these criteria and any poor performance is referred to the Steering Group.

Constitutional Scheme

There are two performance criteria for the Constitutional Scheme: -

  • Constitutional
  • MRA (Molecular Rapid Aneuploidy)

Haemato-Oncology Scheme

There is one set of performance criteria for Haematology and Oncology Cytogenetics.

Haemato-Oncology Performance Criteria

Version 4.3

The Haemato-Oncology Performance Criteria have been updated (June 2008). These criteria are produced by the Steering Committee and agreed by NQAAP (National Quality Assurance Advisory Panel). These criteria are used to mark EQA assessments. They will be used in all EQA assessments from 2008 onwards.

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The Molecular Rapid Aneuploidy (MRA) Performance Criteria

Version 2.0

The MRA (Molecular Rapid Aneuploidy) Performance Criteria have been updated (June 2008). These criteria are produced by the Cytogenetics and Molecular Genetics Steering Committees and agreed by Genetics NQAAP (National Quality Assurance Advisory Panel). These criteria are used to mark EQA assessments. They will be used in all EQA assessments from 2008 onwards.

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Constitutional Performance Criteria

Version 4.5

The Constitutional Performance Criteria have been updated (June 2008). These criteria are produced by the Steering Committee and agreed by NQAAP (National Quality Assurance Advisory Panel). These criteria are used to mark EQA assessments. They will be used in all EQA assessments from 2008 onwards

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