The UK External Quality Assessment Scheme in Clinical Cytogenetics was established in 1982 via the Association of Clinical Cytogeneticists (ACC). In 1983 this scheme became affiliated to, and recognised as a 'pilot' external quality assessment scheme in Clinical Cytogenetics by the UK National External Quality Assessment Schemes (UKNEQAS) Executive.

The scheme is accredited with CPA (UK) Ltd accreditation body.

The aim of the Clinical Cytogenetics Scheme is to improve the overall quality of laboratory services by example and education.

Following assessment, participating laboratories receive a report that includes recognition of good performance, and also constructive criticism where necessary.